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 Research 2005-2003

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Fibrosis Research

2005


Page One:

Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C

July 19, 2005

Etanercept Treatment to Slow Fibrosis Progression Shows No Histological or Biochemical Improvement in Chronic HCV Genotype 1 Nonresponders to Peginterferon/Ribavirin

June 09 2005

Simple Fibrosis Tests May Render Liver Biopsy Unnecessary Only in a Minority of Patients with Chronic HCV

June 09 2005

Long-term Fibrosis Progression in Nonresponders to Interferon-based Therapy

May 30 2005

Baseline Fibrosis Score Does Not Predict SVR to Peginterferon Alfa-2a (Pegasys) Plus Ribavirin in HCV Patients with Persistently ¡°Normal¡± ALT Levels

May 19 2005

Role Of CYP2D6 Polymorphism in Predicting Liver Fibrosis Progression Rate  in Caucasian Patients With Chronic Hepatitis C May 19 2005


Page Two:

Fibrosis Evaluation: Comparison of FibroScan with Liver Biopsy, Fibrotest, Fornscore, Apri, Hyaluronan, Prothrombin Time, and AST/ALT Ratio 

May 03 2005

Screening for Fibrosis with Non-invasive Biomarkers (Fibrotest) in Hyperlipidemic Patients

May 02 2005

Are Current Fibrosis Serum Markers an Adequate Alternative to Liver Biopsy?

May 02 2005

MONITORING LIVER ELASTICITY:  A NEW TOOL TO MEASURE LIVER FIBROSIS DURING THERAPY

April 17 2005

Interferon's Benefits for Fibrosis Studied

Mar 16 2005

Relationship Between Serum Ferritin, Hepatic Iron Staining, Diabetes Mellitus and Fibrosis Progression in Patients with Chronic Hepatitis

Mar 10 2005

Predicting Progressive Fibrosis Stage by Baseline and Subsequent Liver Biopsy

Mar 03 2005

Impact of Steatosis on the Progression of Fibrosis in Patients with Mild Hepatitis

Jan 06 2005

Women May be Protected Against Fibrosis, Suggests Study


    2004

Page Three:


Pegasys/RBV Improves Fibrosis in Responders, relapsers & Nonresponders with Advanced Fibrosis

Dec 06 2004


Page Four:


Peginterferon Alfa-2a (Pegasys) and Ribavirin (Copegus) for the Treatment of Chronic HCV and Compensated Cirrhosis/Fibrosis

11-10-2004

Serum caspase activity and liver fibrosis in patients with hepatitis C

11- 08- 2004

AASLD: Smoking Marijuana Raises Fibrosis Risk in Patients With Chronic Hepatitis C Infection

Daily smoking of cannabis—but not tobacco—associated with more rapid fibrosis in HCV patients

11-02-2004

 


Page Five


Progression of hepatic fibrosis in patients with hepatitis C: a prospective repeat liver biopsy study; 33% showed progression of at least 1 fibrosis point

10-04-04

Long-Term Outcomes in HCV with SVR: cure, regression of fibrosis

 

Fatty Liver Accelerates Fibrosis: diabetes, mitochondrial dyfunction, obesity associated

10-01-04

Impact of competing risks on observed rate of hepatitis C progression

09-24-2004

Natural history of initially mild chronic hepatitis C

Studies on the natural history of initially mild chronic disease indicate that the short-term outcome is always benign. However, progression of liver fibrosis can be observed at long-term (>5–7 years) follow-up, particularly in those cases who have elevated and/or fluctuating transaminase levels.

08/25/2004

Serum Immunoglobulins Predict the Extent of Hepatic Fibrosis in HCV Patients

08/11/2004

Common Heterozygous Hemochromatosis Gene Mutations Are Risk Factors for Inflammation and Fibrosis in Chronic Hepatitis C

08 /11 /2004

Intercept Pharmaceuticals Announces Publication of Study Demonstrating Its Lead Compound Can Reverse Liver Fibrosis

08 /11/ 2004

Hepatic Fibrosis Influences Early Virological Response Rates in Chronic Hepatitis C

06/16/04

 

Viscum Album and Solanum Lycopersicum Inhibit Fibrosis in Chronic Hepatitis C

05/24/04
 

Treatment with Peginterferon Alfa-2b (PEG-Intron) Plus Ribavirin Is Cost-effective for Hepatitis C Patients with F1 Fibrosis

05/24/04

Update on Cirrhosis -- The Role of Fibrosis Markers

05/19/2004

Fibrosis Progression Is Dependent upon Hepatic Inflammation in Chronic Hepatitis C

05-26-04

Factors Associated with HCV Stage 3/4 Fibrosis

05-26-04


Page Six:

2004

March - April 2004


 

    The Severity of Liver Fibrosis Is Associated with High Leptin Levels in Chronic Hepatitis C
    To Evaluate Fibrosis with Liver Biopsy Accurately, a Specimen Length of at Least 25 mm Is Necessary
    Innogenetics study shows improved liver fibrosis in hepatitis C patients
    Long-term Outcome (35 years) of Hepatitis C After Acquisition of Infection Through Mini Blood Transfusions Given at Birth
    Daily Cannabis Smoking as a Risk Factor for Fibrosis Progression in Chronic Hepatitis C
 
    A Sustained Viral Response Predicts a Significant Decrease in Clinical Complications Among Patients with Advanced Fibrosis or Cirrhosis

Insulin Resistance, Fibrosis and Genotype Independently Predict the Sustained Response Rate (SVR) to Therapy with Pegylated Interferon Plus Ribavirin

   

Page Seven:


Predicting progression to cirrhosis in chronic hepatitis C virus infection

    A comparison in the progression of liver fibrosis in chronic hepatitis C between persistently normal and elevated transaminase
    Biochemical Markers Accurately Predict Significant Fibrosis
    Fibrosis and Disease Progression in Hepatitis C
    The Natural History of Fibrosis in Chronic Hepatitis C: Older Age at Infection Onset and Increasing Duration of infection are Primary Determinants of Fibrosis Progression
   

Page Eight:


The Role of Antiviral Therapy in the Natural History
of Hepatitis C Fibrosis

    PEG interferon and ribavirin reduce liver fibrosis rate in hepatitis C
    Natural history of liver fibrosis in hepatitis C virus infection
    Fibrosis what does it mean ?
    Diagnosing fibrosis in hepatitis C: Is the pendulum swinging from biopsy to blood tests? (see Editorial below by Nezam Afdahl, MD)

 

 

 

 

 
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Reviewed Jan 05 2006