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2007

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Dec 2007

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2004-2001 Research Archives


Cancer Surveillance Futile in Advanced Cirrhosis

Non-invasive FibroTest and FibroScan Predict Liver Cirrhosis Better than Earlier Stages of Fibrosis in Hepatitis C Patients

Eltrombopag for Thrombocytopenia in Patients with Cirrhosis Associated with Hepatitis C -

Treating Patients with Cirrhosis

Non-Invasive Tests for Cirrhosis May Help to Avoid Liver Biopsy

Nexavar First FDA-Approved Drug Therapy for Liver Cancer

HCV Treatment Aided by New Platelet-Boosting Drug


Nov 2007


Clinical Relevance of Rapid Virological Response (RVR) in Decompensated HCV-Related Cirrhosis Treated With Peginterferon and Ribavirin

MAINTENANCE THERAPY FOUND INEFFECTIVE HALT-C STUDY

Hepatitis C and Decompensated Cirrhosis Improve With Combination Therapy, Individualized Approach: Presented at AASLD

What is the best non invasive method for early prediction of cirrhosis in chronic hepatitis C? Prospective comparison between Fibroscan and serum markers (Lok index, APRI, AST/ALT ratio, platelet count and Fibrotest) -

Danazol Increases Platelet Counts in Thrombocytopenia Patients with Chronic Hepatitis C or Cirrhosis -

Positive Impact of Antiviral Therapy on the Long Term Outcome of Chronic Hepatitis C Patients with Cirrhosis

Consensus Interferon in Hepatitis C Is an Option for Those Non-Responsive to Peginterferon/Ribavrin: Presented at AASLD

Long-term prognosis of elderly patients with hepatitis C virus-related chronic liver disease --- A cohort study of 2,379 Japanese patients

Hepatocellular carcinoma in long-term sustained virologic responders to antiviral treatment for chronic hepatitis C

Treatment of Hepatitis C Patients with Child A and B cirrhosis with Consensus Interferon and Ribavirin in a Low Ascending Dosing Regimen Leads to Significant Viral Elimination Rates

Bone mineral density and metabolism in non-cirrhotic patients with chronic hepatitis C before and after antiviral therapy with pegylated interferon α and ribavirin: a prospective controlled study

Clinical Relevance of Rapid Virological Response (RVR) in Decompensated HCV-Related Cirrhosis Treated with PEG-Interferon and Ribavirin

Long-Term, Low-Dose Treatment With Pegylated Interferon alfa-2b Leads to a Significant Reduction in Fibrosis and Inflammatory Scores in Chronic Hepatitis C Nonresponder Patients With Fibrosis or Cirrhosis


HCV Advocate’s AASLD NOV 2007 Conference coverage

Nov 2007  Disease Progression: 

 Various factors that influence HCV disease progression including steatosis, obesity, insulin resistance, diabetes, race/ethnicity, and general studies on disease progression.


·        General

o       1330. Effects of chronic HCV infection on health-related quality of life and fatigue: the role of liver fibrosis progression (updated November 6, 2007)

o       1336. Tracking the Course of Hepatitis C with Paired Biopsies - A Critical Analysis (updated November 6, 2007)

o       1337. Long-term Morbidity and Mortality of HCV Infection: A 25 years Follow-up

o       1340. Histological Outcomes After 30 Years In Untreated Irish Women With Chronic HCV Genotype 1b, Do Genetic Factors Influence? (updated November 6, 2007)

o       1341. Higher Caffeine Consumption is associated with Milder Fibrosis in patients with Chronic Liver Diseases

o       1347. Obesity is an Independent predictor of fibrosis progression in patients with chronic Hepatitis C Virus (HCV) using paired liver biopsy specimens (updated November 6, 2007)

o       1360. Cause of Death in Patients with Hepatitis C (HCV)-Mixed Cryoglobulinemia (MC) Vasculitis

o       1366. Host rather than viral factors reduce health-related quality of life in hepatitis C virus infection

 

·        Hepatocellular Carcinoma

o       133. Chronic hepatitis C virus infection and risk of hepatocellular carcinoma: a community-based prospective study on 19,565 residents in Taiwan

 

·        Metabolic disorders

o       533. High Prevalence of Glomerulonephritis in Patients with End-stage HCV-induced Cirrhosis

 

·        Race

o       354. The Role of Steatosis and Diabetes as a Predictor of Treatment Response to Interferon Based Therapies in Latino Americans with Chronic Hepatitis C

 

·        Steatosis

o       301. The Impact Of Steatosis And Steatohepatitis On The Response To Treatment In Patients With Chronic Hepatitis C Infection

 


Oct 2007


Cirrhosis in the Medical Intensive Care Unit - 1 of 4

Cirrhosis in the Medical Intensive Care Unit - Management of the Patient With Cirrhosis and Acute GI

Cirrhosis in the Medical Intensive Care Unit - Management of the Patient With Cirrhosis and Altered

Cirrhosis in the Medical Intensive Care Unit - Management of the Patient With Cirrhosis and Infection 

Researching Cure For Liver Cirrhosis

Predictors of Mortality in Hepatic Encephalopathy in Acute and Chronic Liver Disease: A Preliminary

Propranolol Better First-Line Prophylaxis Than Ligation for Variceal Bleeding

Insulin Resistance and Diabetes

Minimal Hepatic Encephalopathy Associated With Increased Traffic Accidents

FDA Safety Changes: Copegus, Intron A

Noninvasive Tests For Cirrhosis May Help To Avoid Liver Biopsy

Monitoring HIV Disease Progression in People with Cirrhosis

Anti-Cancer Drug PI-88 Awarded Fast Track Status by the Food and Drug Administration


Sept-Aug-July-June 2007


The Use of Transient Elastometry for Assessing Liver Fibrosis in Patients with HIV and Hepatitis C Virus Coinfection: only detects cirrhosis

Prolonged Interferon Therapy May Prevent Progression of Hepatitis C to Cancer

Symptoms of Liver Disease & Risk Factors for Upper GI Bleeding

New Marker for Liver Cancer May Allow for Earlier Detection

  Driving With Minimal Hepatic Encephalopathy: Real World Consequences?

Patients with Depression prior to Hepatitis C Treatment Are Half as Likely to Achieve Sustained Virological Response

 Muscular exercise can cause highly pathological liver function tests in healthy

Coffee Consumption May Reduce the Risk of Liver Cancer

IAS: Atazanavir safe and effective in HCV-coinfected patients with cirrhosis

Stanford researchers develop new genetic marker test to predict likelyhood for progression to cirrhosis of hcv patients:

Mitochondrial Toxicity

ABC of diseases of liver, pancreas, and biliary system: Portal hypertension-1: varices

Obesity 'No. 1 liver issue'

Liver tonics not sure guard against liver diseases

Atorvastatin (Lipitor) lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase -

Natural History of Hepatitis C in Patients with Severe Liver Fibrosis

Ursodeoxycholic Acid May Reduce Liver Inflammation in Patients with Chronic Hepatitis C   

Liver Enzyme Flares and Occult HBV Infection in Patients with Untreated Chronic Hepatitis C   

The Emotional Impact of Leaving Work on Disability

New Data Suggest that Patients with Chronic Liver Disease are at Increased Risk for Heart Disease

Association of Hepatitis C Seropositivity With Increased Risk for Developing End-stage Renal
Disease.

New acute liver failure research from University of Texas, Department of Internal Medicine outlined

Milk Thistle (Silymarin) Demonstrates Anti-inflammatory and Anti-HCV Activity in a Laboratory Study

Body composition, muscle function, and energy expenditure in patients with liver cirrhosis: a comprehensive study

Treatment with Pegasys Plus Ribavirin in Genotype 2/3 Chronic Hepatitis C Patients with Liver Cirrhosis

Transient Elastography as a Non-invasive Method for Predicting Portal Hypertension in Patients with Hepatitis C-related Cirrhosis

A Follow-up Week 12 Viral Count Is Useful in Predicting SVR and Is 100% Accurate in Patients without Cirrhosis

Early Pegasys/RBV Therapy is Cost Effective, Improves Survival & Reduces Risk for Cirrhosis -

Cost-effectiveness, Survival, and Prevention of Cirrhosis with Early Treatment of Chronic Hepatitis C with Peginterferon Alfa-2a (40KD) plus Ribavirin before Progression to Advanced Liver Disease -

Reversibility of hepatic fibrosis and cirrhosis-is it all hype? Editorial

Glucose Intolerance Associated with Advancing Liver Disease (Fibrosis)

Body composition, muscle function, and energy expenditure in patients with liver cirrhosis: a comprehensive study


May 2007



Sustained virological response to interferon reduces cirrhosis in chronic hepatitis C: a 1386-patient
study from Taiwan.

Response to PegIntron/ribavirin Leads to Stabilization of Fibrosis in Liver Transplant Recipients

 Treatment of hepatitis C virus infection.

Does SVR after Treatment with Pegasys/ribavirin Constitute a Cure for Chronic Hepatitis C?


April-March 2007


Schering's Experimental Oral HCV Protease Inhibitor Boceprevir Appears Safe in Patients with Varying Degrees of Liver Impairment  -

Roche Driving PROGRESS in Treatment of Difficult-to-Cure Hepatitis C Patients With New PEGASYS (R) (peginterferon alfa-2a (40KD)) and COPEGUS(R) (ribavirin) Trial -

Interferon Gamma Does Not Reverse Fibrosis in Hepatitis C Patients with Advanced Liver Disease

Sustained Response to Interferon Monotherapy Reduces Rates of Liver Cancer and Death in Patients with HCV-related Cirrhosis  

Peginterferon alfa-2b and ribavirin in patients with hepatitis C virus and decompensated cirrhosis: A controlled study -

Improving Quality Of Life For Patients With Cirrhosis

Liver problems: Common problems and how to avoid them

Health-related Quality of Life in Chronic Hepatitis C Patients with Advanced Fibrosis

Impact of Reducing Peginterferon Alfa-2a and Ribavirin Dose During Retreatment in Patients With Chronic Hepatitis C (HALT-C Study) -

From Our Message boards

CIRRHOSIS

February

Impact of Cirrhosis on CD4 Cell Counts in HIV Negative Individuals Has Implications for HIV-HCV and HIV-HBV Coinfected Patients

Rapamycin Reduces Fibrosis and Improves Liver Function in Rats

December-January

Liver transplant: Treating end-stage liver disease

HCV Continues to Replicate in the Livers of Patients with Sustained Response to Therapy
 

Treatment of Hepatitis C in Patients with Advanced Fibrosis or Cirrhosis
 

Impact of Disease Severity on HCV Treatment Outcomes in HALT-C Trial


Treatment Response in Cirrhotic Hepatitis C Patients with Portal Hypertension

In the new area of noninvasive markers of hepatocellular carcinoma

Pathogenesis of osteoporosis in liver cirrhosis

You Are Invited: Clinical Care Options for Hepatitis Symposium 2007


2008 Research   2007 Research

2006 Research    2005 Research  

2004-2001 Research Archives

 

Reviewed Dec15  07

 
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