This Web Site is committed to the memory of Janis Morrow.
Transplants
2009
Before you're listed/medications/living donation/questions to ask
MELD Score and the Question of When I am Getting My Liver?
July
What I
need to know about Liver Transplantation
http://www.foodconsumer.org
Steve Jobs, co-founder and CEO of Apple Inc. received a liver transplant in Tennessee about two months ago, Wall Street Journal reported Friday. Jobs has been on medical leave since January to treat a undisclosed medical condition. He has reportedly been recovering well and is expected to return to work soon.
Cited below is an article on liver transplant from a U.S. government website for those who might be interested in knowing more about the procedure.
What I need to know about Liver
Transplantation
http://digestive.niddk.nih.gov/ddiseases
/pubs/livertransplant_ez/
Liberal selection criteria for liver transplantation forhepatocellular carcinoma
FYI...Artificial Liver For Drug Tests
Acetaminophen and Liver Injury: Q & A for Consumers
FDA Takes Action on Acetaminophen
Microproteinuria: Indicator To Monitor CNI-Related Nephrotoxicity In Liver Transplant Recipients?
June
For HCV-Positive Liver Transplant Recipients, Some Donor Factors Affect Outcomes
Nanotechnologist Creates Liver on a Computer Chip
Close to 20,000 Americans are waiting for a liver transplant - and some will die before they get one. A transplant is still the only hope for anyone with hepatitis C or liver cancer. That's because developing the right drugs to treat liver disease has been a struggle for researchers. One nanotechnologist is changing that.
Strategies for Managing Acetaminophen-related Liver Disease and Acute Liver Failure
Liver disease: Better monitoring, better prognosis
High-Tech Artificial Liver Extends Lives
"More than 27,000 people die every year from liver disease while only 6,000 receive new livers. A new artificial liver may close this gap.
May
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Acute Kidney Injury Common After Liver Transplantation
Survival Rates Following Liver Transplant Similar In HIV Positive And HIV Negative Patients
Diabetes, Obesity And Hypertension Increase Mortality In Hepatitis C Patients
Warning on Hydroxycut Products
Liver Cancer Drug Sorafenib (Nexavar) May Also Alleviate Complications Due to Cirrhosis
EASL: Maintenance Therapy: we don't know if it provides benefit -
EASL: EPIC Study Shows Maintenance Therapy Provides Benefits -
Transplanted Liver Cells Function In Older Animals But Do Not Proliferate As Much As In Younger Ones
April-March
Genetically Mismatched Liver Transplants Predict HCV Recurrence, Progression
Preventing Bleeding Varices: A Liver Transplant Must
Licorice May Block Effectiveness Of Drug Widely Used By Transplant Patients
The Immune System's Role In Hepatitis C Recurrence After Liver Transplantation
The evaluation of liver dysfunction: When to suspect portal hypertension
4-01
MELD and other predictors of liver transplant survival14 April 2009 |
| This month’s issue of Clinical Transplantation investigates MELD and other predictors of survival after liver transplantation. |
| Dr Ajacio Brandão and colleagues from Brazil examined how reliable the pre-transplant model is for end-stage liver disease (MELD) score in predicting post-transplantation survival. In addition, the research team analyzed variables associated with patient survival. The team conducted a cohort study using receiver operating characteristic curve c-statistics to determine the ability of MELD score to predict mortality. The Kaplan–Meier method was used to analyze survival as a function of time regarding the MELD score and Child-Turcotte-Pugh category. The Cox model was employed to assess the association between baseline risk factors and mortality. The researchers identified 436 transplants, and that recipients and donors were mostly male, with a mean age of 52 and 39 years, respectively. The c-statistic values for three-month patient mortality were 0.60 and 0.61 for MELD score and Child-Turcotte-Pugh category, respectively. Kaplan–Meier survival at 3, 6 and 12 months were lower in those who had a MELD score of 21 or were Child-Turcotte-Pugh category C. Multivariate analysis revealed that recipient age 65 years, MELD score of 21, Child-Turcotte-Pugh C category, and a bilirubin level of 7 mg/dL were predictors of mortality. Creatinine levels of 1.5 mg/dL, platelet transfusion, hepatocellular carcinoma, and non-white color donor skin were also predictors of mortality. Dr Brandão’s team concluded, “Severe pre-transplant liver disease, age 65 years, non-white skin donor, and hepatocellular carcinoma are associated with poor outcome.” |
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Clin Transplant 2009: 23(2): 220-7 14 April 2009 |
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Post-liver transplant survival in hepatitis C patients is improving over time
Wrestlemania XXV: Recalling the lords of the ring
HCV Treatment after Liver Transplantation
Liver transplants succeed in many hepatitis C patients
Donor gives Lower Burrell woman 'second birthday'
February-January
Hepatitis C Patients Should Avoid Fatty
Liver Transplants.
Treatment of hepatitis C in liver transplant recipients
Statement On Liver Transplants - Royal
Free Hampstead NHS Trust, England
In light of recent press reports about liver transplants
at the Royal Free Hampstead NHS Trust, we would like to
make the following points:- 1. There is no truth in the
assertion that patients from outside the UK can 'buy'...
[read
article]
Link Between Transplanted Fatty Livers And Worse Prognosis For Patients With HCV
ELAD(R) Liver Support System Study Initiated at Multiple U.S. Centers
Mayo Clinic Researchers Develop Improved Tool to Rank Sickest Patients Waiting for Liver Transplants
AASLD New Approach Urged for Liver Transplant Allocation
Impact of donor graft steatosis on overall outcome
and viral recurrence after liver transplantation for hepatitis C
virus cirrhosis
The aim of this study was to determine the influence of donor graft
steatosis on overall outcome, viral recurrence, and fibrosis
progression in orthot...
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Cirrhosis of mixed etiology (hepatitis C virus and
alcohol): Posttransplantation outcome-Comparison with hepatitis C
virus-related cirrhosis and alcoholic-related cirrhosis
Hepatitis C virus (HCV)-related liver disease is enhanced by alcohol
consumption. Of HCV-related liver transplantation (LT) recipients,
25% have a his...
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Long-term antiviral therapy for recurrent hepatitis C
after liver transplantation in nonresponders: Biochemical,
virological, and histological impact
More than 50% of patients with a recurrent posttransplant hepatitis
C virus infection fail to respond to antiviral treatment. The aim of
this study wa...
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‘Miracle man’ from Halifax survives three transplants
Molecular Events Involved In Liver Regeneration
The ability to regenerate after major tissue damage or surgical
intervention is an important property of the liver. Since liver
resection is an established therapeutic measure for severe liver
diseases, it would be of...
[read
article]
Liver transplants from elderly donors are safe
Posted on December 29th 2008
Advanced donor age, per se, does not adversely affect the transplant
recipient or the survival of the organ after liver transplantation,
according to a report in the Journal of
the American College of Surgeons.
Management of Hepatitis C in the Pre-Transplant Patient