Inhibitors & New Therapies

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2008


April


Janis and Friends Forum: Read and Comment on EASL Coverage.

VX950 Protease Inhibitor Telaprevir

New HCV Drugs Panel Discussion at EASL 2008

Safety of the HCV Protease Inhibitor TMC435350 in Healthy Volunteers and Safety and Activity in Chronic Hepatitis C Infected Individuals: A Phase I Study

HCV Protease Inhibitor Telaprevir, PROVE1 Study: final results of a phase 2 study with peginterferon plus ribaviron in treatment-naive patients with hepatitis C -

ONCE-DAILY REGIMENS OF THE HCV NS3/4A-PROTEASE INHIBITOR TMC435350 ARE PREDICTED TO PROVIDE THERAPEUTIC EXPOSURE IN PLASMA AND LIVER -

Interim Results from HCV SPRINT-1: RVR/EVR from Phase 2 Study of Boceprevir Plus Peginterferon alfa-2b/Ribavirin in Treatment-Naive Subjects with Genotype-1 CHC

DEVELOPMENT OF NOVEL HYPERGLYGOSYLATED TYPE 1 INTERFERONS: A STRATEGY TO IMPROVE PK PERFORMANCE WITHOUT LOSS OF BIOLOGICAL POTENCY

Boceprevir (NS3 Protease Inhibitor) Combination Therapy in Non Responders: Phase II Dose Finding Study -

Sustained Viral Response Is Dependent On Baseline Characteristics In The Re-treatment Of Previous Interferon/Ribavirin Non-responders: Final Results From The EPIC3 Program

Romark Announces Presentation of New Data For Nitazoxanide in Chronic Hepatitis C at EASL 2008 -

Pharmasset Presents Results of 4-Week Combination Study of R7128 for the Treatment of Chronic Hepatitis C -

Potent Antiviral Activity of 2nd Generation HCV Nucleotide Inhibitors, IDX102 and IDX184, in HCV-infected Chimps

In Vitro Activity and Pharmacologic Properties of Two Novel Series of HCV Protease Inhibitors -

Efficacy and safety of increasing doses of the cyclophilin inhibitor Debio 025 in combination with pegylated interferon alpha-2a in treatment naive chronic HCV patients -

Safety of the HCV Protease Inhibitor TMC435350 in Healthy Volunteers and Safety and Activity in Chronic Hepatitis C Infected Individuals: A Phase I Study

InterMune Provides Additional Information on ITMN-191 (R7227) MAD Study Results

ONCE-DAILY REGIMENS OF THE HCV NS3/4A-PROTEASE INHIBITOR TMC435350 ARE PREDICTED TO PROVIDE THERAPEUTIC EXPOSURE IN PLASMA AND LIVER -

Telaprevir plus Pegylated Interferon and Ribavirin Allows Shorter Therapy for Patients with Genotype 1 HCV

Gilead Announces 72-Week Data from Pivotal Studies of Tenofovir (Viread) for Chronic Hepatitis B

Biolex Therapeutics Researchers Present Locteron(R) Phase 2a Hepatitis C Trial Results at EASL Conference

Pharmasset Adds Two Cohorts to R7128 Hepatitis C Study

Vertex reports promising hepatitis C drug results

Vertex Telaprevir HCV Protease Inhibitor Could Be A Winner; 2.5 million untreated/undiagnosed

Valeant Reports Promising 12-week Phase IIb Data on Taribavirin -

Vertex and Tibotec Start Phase 3 Study of Telaprevir for Treatment-Naive Genotype 1 Hepatitis C Patients

OctoPlus Initiates Phase IIa Study of Locteron Controlled-release Interferon


March-February


HCV Therapy: TT-033, novel RNA interference product Oncolys and Tacere partner in hepatitis C drug development

Human Genome Shares Dip on Drug Outlook

The way forward in HCV treatment - finding the right path: New HCV Drugs, resistance -

Vertex to Start Phase 3 Trials of HCV Protease Inhibitor Telaprevir (VX-950)

 


Jan


Vertex Pharmaceuticals to Begin Phase 3 Development of Telaprevir, Investigational Hepatitis C Protease Inhibitor

Albuferon Dose in Ongoing Trials is Lowered Due to Safety Concerns

InterMune Announces Continuing Progress on HCV Protease Inhibitor ITMN-191 (R7227)

Anadys Pharmaceuticals Announces Positive Results for ANA598 in Animal Model of Chronic Hepatitis C Virus Infection

Pharmasset Announces R7128 Achieves 85% Rapid Virologic Response in a 4-week Combination Study for the Treatment of Chronic Hepatitis C

 

 

 

   
 
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Reviewed Apr 25 2008